Sage with Lost grid system

I want to Learn lost, and since Sage is my prefered model I’ll have to ask if there are anything I should think about regarding this combination?

Is it enough to just add and require postcss and then pipe it? Anything I should know and think about?

var postcss = require(‘gulp-postcss’);

.pipe(postcss([
lost(),
autoprefixer({ browsers: [‘last 2 versions’] })
]))