@timothy_m_alber I think there are a number of discourse threads you could search and find on the topic. One that comes to mind that might be relevant is How to create subdomain on digital ocean correctly?
That demonstrates having multiple sites within wordpress_sites, each with their respective variables. Let us know if you also need different vars files per site, which would be unusual.
Edit. I may have misunderstood. I was thinking the paths you listed were referring to filepaths of your trellis project structure, like how you might alter the Trellis project structure mentioned in the Trellis installation docs to accommodate multiple WordPress sites all hosted on a single server as separate WP installs. But maybe the paths you mentioned were actually referring to URLs for a WP multisite setup using subdirectories (?).