Running a Local Wordpress with InstantWP

i use InstaWP to run a localmachine wordpress installation inkl. mysql etc.

does it totaly work with the root setup?
grunt, capistrano, theme activation, permalinks etc…

anyone has an experience on this?

No experience on this, but it looks like it might be able to work.

You will still have to have node/grunt on your local machine to compile the js and less files. Capistrano is a ruby application so you’d have to have that on your machine as well.

Best thing for you to do would be to try it out!
I however, would take the time to install vagrant and then use VVV to host my local dev environment. That way you know what’s going on and you could run grunt from there.